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Fig. 8. Zebrafish Ae2 mediates Cl^–/HCO₃^– exchange. A: changes in pH_i measured in representative BCECF-loaded Xenopus laevis oocytes in the presence of CO₂/HCO₃^– during bath Cl^– removal and restoration. Oocytes were previously injected with water or with 3 or 10 ng ae2 cRNA as indicated. B: mean rates of Cl^–/HCO₃^– exchange ± SD presented as proton-equivalent flux (J_H+).