AJP - Renal Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Renal Physiol 263: F175-F179, 1992;
0363-6127/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Feraille, E.
Right arrow Articles by Doucet, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Feraille, E.
Right arrow Articles by Doucet, A.

AJP - Renal Physiology, Vol 263, Issue 1 175-F179, Copyright © 1992 by American Physiological Society

ARTICLES

Sites of antinatriuretic action of insulin along rat nephron

E. Feraille, S. Marsy, L. Cheval, C. Barlet-Bas, C. Khadouri, H. Favre and A. Doucet
Laboratoire de Physiologie Cellulaire, College de France, Paris.

This study was aimed at identifying the renal sites of the antinatriuretic action of insulin by evaluating whether this hormone may alter the function of Na-K-ATPase in specific nephron segments. For this purpose, possible actions of insulin on the rate of 86Rb uptake were evaluated in vitro on single segments of proximal convoluted tubule (PCT), thick ascending limb, and collecting tubule microdissected from collagenase-treated kidneys of normal rats. Results indicate that physiological concentrations of insulin inhibited by 44% the initial rate of ouabain-sensitive 86Rb uptake in the medullary and cortical thick ascending limb, whereas it increased it by 40% in proximal tubules and by 60% in both cortical and medullary collecting tubules. The kinetics and dose dependence of insulin actions were different in the thick ascending limb, the PCT, and the collecting tubule, with the latter less sensitive but displaying an earlier response to insulin than the PCT and the thick ascending limb.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Renal Physiol.Home page
U. Hasler, V. Leroy, P.-Y. Martin, and E. Feraille
Aquaporin-2 abundance in the renal collecting duct: new insights from cultured cell models
Am J Physiol Renal Physiol, July 1, 2009; 297(1): F10 - F18.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
S. Tiwari, S. Riazi, and C. A. Ecelbarger
Insulin's impact on renal sodium transport and blood pressure in health, obesity, and diabetes
Am J Physiol Renal Physiol, October 1, 2007; 293(4): F974 - F984.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
S. Tiwari, L. Nordquist, V. K. M. Halagappa, and C. A. Ecelbarger
Trafficking of ENaC subunits in response to acute insulin in mouse kidney
Am J Physiol Renal Physiol, July 1, 2007; 293(1): F178 - F185.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
M. Bustamante, U. Hasler, O. Kotova, A. V. Chibalin, D. Mordasini, M. Rousselot, A. Vandewalle, P.-Y. Martin, and E. Feraille
Insulin potentiates AVP-induced AQP2 expression in cultured renal collecting duct principal cells
Am J Physiol Renal Physiol, February 1, 2005; 288(2): F334 - F344.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
N. Y. Tallini and L. C. Stoner
Amiloride-sensitive sodium current in everted Ambystoma initial collecting tubule: short-term insulin effects
Am J Physiol Cell Physiol, October 1, 2002; 283(4): C1171 - C1181.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
S. Gonin, G. Deschênes, F. Roger, M. Bens, P.-Y. Martin, J.-L. Carpentier, A. Vandewalle, A. Doucet, and E. Féraille
Cyclic AMP Increases Cell Surface Expression of Functional Na,K-ATPase Units in Mammalian Cortical Collecting Duct Principal Cells
Mol. Biol. Cell, February 1, 2001; 12(2): 255 - 264.
[Abstract] [Full Text]

Home page
 Physiol. Rev.Home page
L.-J. Dai, G. Ritchie, D. Kerstan, H. S. Kang, D. E. C. Cole, and G. A. Quamme
Magnesium Transport in the Renal Distal Convoluted Tubule
Physiol Rev, January 1, 2001; 81(1): 51 - 84.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
E. Feraille and A. Doucet
Sodium-Potassium-Adenosinetriphosphatase-Dependent Sodium Transport in the Kidney: Hormonal Control
Physiol Rev, January 1, 2001; 81(1): 345 - 418.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
J. C. ter Maaten, E. H. Serne, W. S. van Eps, P. M. ter Wee, A. J. M. Donker, and R. O. B. Gans
Effects of insulin and atrial natriuretic peptide on renal tubular sodium handling in sickle cell disease
Am J Physiol Renal Physiol, March 1, 2000; 278(3): F499 - F505.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
L.-J. Dai, G. Ritchie, B. W. Bapty, D. Kerstan, and G. A. Quamme
Insulin stimulates Mg2+ uptake in mouse distal convoluted tubule cells
Am J Physiol Renal Physiol, December 1, 1999; 277(6): F907 - F913.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
E. Féraille, M. L. Carranza, S. Gonin, P. Béguin, C. Pedemonte, M. Rousselot, J. Caverzasio, K. Geering, P.-Y. Martin, and H. Favre
Insulin-induced Stimulation of Na+,K+-ATPase Activity in Kidney Proximal Tubule Cells Depends on Phosphorylation of the alpha -Subunit at Tyr-10
Mol. Biol. Cell, September 1, 1999; 10(9): 2847 - 2859.
[Abstract] [Full Text]

Home page
 HypertensionHome page
B. Grunfeld, M. Gimenez, M. Balzaretti, L. Rabinovich, M. Romo, and R. Simsolo
Insulin Effect on Renal Sodium Reabsorption in Adolescent Offspring of Essential Hypertensive Parents
Hypertension, December 1, 1995; 26(6): 1089 - 1092.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online