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Am J Physiol Renal Physiol 275: F328-F331, 1998;
0363-6127/98 $5.00
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Vol. 275, Issue 3, F328-F331, September 1998

BRIEF REVIEW
Cellular mechanisms of aquaporin trafficking1

Dennis Brown, Toshiya Katsura, and Corinne E. Gustafson

Renal Unit and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129

Aquaporins (AQPs) are a family of functionally important water channel proteins that are of special cell biological interest because of their diverse intracellular targeting and trafficking properties. AQPs have been found in many different cells and tissues. This short review summarizes recent work that addresses the regulation of AQP2 trafficking in response to vasopressin.

vasopressin; phosphorylation

1 This report is the third in a series of minireviews, which are based on a symposium on the urinary concentrating mechanism, held at Experimental Biology '97 in New Orleans, LA.




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