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Am J Physiol Renal Physiol 287: F866-F867, 2004; doi:10.1152/classicessays.00019.2004
0363-6127/04 $5.00

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EDITORIAL FOCUS

ESSAYS ON APS CLASSIC PAPERS

Micropuncture: unlocking the secrets of renal function

Renal Division, Department of Medicine, and Department of Physiology, Emory University School of Medicine, Atlanta, Georgia 30322

ABSTRACT

This essay looks at the historical significance of five APS classic papers that are freely available online:

Wearn JT and Richards AN. Observations on the composition of glomerular urine, with particular reference to the problem of reabsorption in the renal tubules. Am J Physiol 71: 209—227, 1924 (http://ajplegacy.physiology.org/cgi/reprint/71/1/209).

Richards AN and Walker AM. Methods of collecting fluid from known regions of the renal tubules of Amphibia and of perfusing the lumen of a single tubule. Am J Physiol 118: 111—120, 1936 (http://ajplegacy.physiology.org/cgi/reprint/118/1/111).

Walker AM and Hudson CL. The reabsorption of glucose from the renal tubule in Amphibia and the action of phlorhizin upon it. Am J Physiol 118: 130—143, 1936 (http://ajplegacy.physiology.org/cgi/reprint/118/1/130).

Walker AM and Oliver J. Methods for the collection of fluid from single glomeruli and tubules of the mammalian kidney. Am J Physiol 134: 562—579, 1941 (http://ajplegacy.physiology.org/cgi/reprint/134/3/562).

Walker AM, Bott PA, Oliver J, and MacDowell MC. The collection and analysis of fluid from single nephrons of the mammalian kidney. Am J Physiol 134: 580—595, 1941 (http://ajplegacy.physiology.org/cgi/reprint/134/3/580).

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