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Am J Physiol Renal Physiol 287: F868-F870, 2004; doi:10.1152/classicessays.00009.2004
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EDITORIAL FOCUS

ESSAYS ON APS CLASSIC PAPERS

The development of clearance methods for measurement of glomerular filtration and tubular reabsorption

¹National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892; and ²Stanford University School of Medicine, Department of Medicine, Division of Nephrology, Palo Alto Veterans Affairs Health Care System, Palo Alto, California 94303

ABSTRACT

This essay looks at the historical significance of four APS classic papers that are freely available online:

Jolliffe N, Shannon JA, and Smith HW. The excretion of urine in the dog. III. The use of non-metabolized sugars in the measurement of the glomerular filtrate. Am J Physiol 100: 301—312, 1932 (http://ajplegacy.physiology.org/cgi/reprint/100/2/301).

Shannon JA. The excretion of inulin by the dog. Am J Physiol 112: 405—413, 1935 (http://ajplegacy.physiology.org/cgi/reprint/112/3/405).

Shannon JA and Fisher S. The renal tubular reabsorption of glucose in the normal dog. Am J Physiol 122: 765—774, 1938 (http://ajplegacy.physiology.org/cgi/reprint/122/3/765).

Shannon JA, Farber S, and Troast L. The measurement of glucose Tm in the normal dog. Am J Physiol 133: 752—761, 1941 (http://ajplegacy.physiology.org/cgi/reprint/133/3/752).

Addresses for correspondence: T. W. Meyer, Stanford Univ. School of Medicine, Dept. of Medicine, Division of Nephrology, Palo Alto VAHCS, 3801 Miranda Ave, Palo Alto, CA 94303 (E-mail: twmeyer{at}stanford.edu)

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