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Am J Physiol Renal Physiol 291: F1109-F1112, 2006; doi:10.1152/classicessays.00311.2006 Free Article
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EDITORIAL FOCUS

Significance of urea transport: the pioneering studies of Bodil Schmidt-Nielsen

Juha P. Kokko1 and Jeff M. Sands1,2

1Renal Division, Department of Medicine, and 2Department of Physiology, Emory University School of Medicine, Atlanta, Georgia

This essay looks at the historical significance of five APS classic papers that are freely available online:

MURDAUGH HV JR, SCHMIDT-NIELSEN B, DOYLE EM, AND O'DELL R.: Renal tubular regulation of urea excretion in man. J Appl Physiol 13: 263–268, 1958. (http://jap.physiology.org/cgi/reprint/13/2/263)

SCHMIDT-NIELSEN B.: Renal tubular excretion of urea in kangaroo rats. Am J Physiol 170: 45–56, 1952. (http://ajplegacy.physiology.org/cgi/reprint/170/1/45)

SCHMIDT-NIELSEN B.: Urea excretion in white rats and kangaroo rats as influenced by excitement and by diet. Am J Physiol 181: 131–139, 1955. (http://ajplegacy.physiology.org/cgi/reprint/181/1/131)

SCHMIDT-NIELSEN B, OSAKI H, MURDAUGH HV JR, AND O'DELL R.: Renal regulation of urea excretion in sheep. Am J Physiol 194: 221–228, 1958. (http://ajplegacy.physiology.org/cgi/reprint/194/2/221)

TRUNIGER B AND SCHMIDT-NIELSEN B.: Intrarenal distribution of urea and related compounds: effect of nitrogen intake. Am J Physiol 207: 971–978, 1964. (http://ajplegacy.physiology.org/cgi/reprint/207/5/971)


Address for reprint requests and other correspondence: J. M. Sands, Emory Univ. School of Medicine, Renal Division, WMRB Rm. 338, 1639 Pierce Drive, NE, Atlanta, GA 30322 (e-mail: jsands{at}emory.edu)






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