Engagement of the otolith organs elicits differential activation of sympathetic nerve activity and vascular responses to muscle and skin in humans. Additionally, aging attenuates the otolith organ-mediated increases in muscle sympathetic nerve activity in older adults. In this study, we hypothesized that 1) the vestibulosympathetic reflex (VSR) would elicit visceral vascular vasoconstriction and 2) visceral vascular response to the VSR would be attenuated in older subjects as compared to young. To test these hypotheses, heart rate, mean arterial blood pressure, and renal, celiac trunk and superior mesenteric arterial blood velocity (Doppler ultrasound) were measured in twenty-two young (25±1 yrs) and eighteen older (65±2 yrs) healthy subjects during head-down rotation (HDR), which selectively activates the otolith organs. Mean arterial pressure and heart rate did not change from baseline during HDR in young or older subjects. Renal blood velocity (-2±1 cm/s) and vascular conductance (-0.03±0.01 cm/s/mmHg) significantly decreased from baseline during HDR (p<0.05) in young subjects. In contrast, renal blood velocity and conductance did not change in older subjects (-0.2±1 cm/s and 0.02±0.08 mmHg/cm/s, respectively) during HDR. Superior mesenteric and celiac blood velocity and vascular conductance did not change in response to HDR in either the young or older subjects. These data suggest that renal vasoconstriction occurs during otolith organ activation in young but not older humans. Together with our previous studies, we conclude that the VSR elicits a diverse patterning of sympathetic outflow which results in heterogeneous vascular responses in humans and that these responses are significantly attenuated in older humans.