EDITORIAL FOCUS:

R. Tyler Miller

Phospho-specific antibodies: more valuable than originally thought
Am J Physiol Renal Physiol 289: F247-F248, 2005; doi:10.1152/ajprenal.00077.2005 [Full Text] [PDF]  

Hetal S. Kocinsky, Adriana C. C. Girardi, Daniel Biemesderfer, Thao Nguyen, SueAnn Mentone, John Orlowski, and Peter S. Aronson

Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na⁺/H⁺ exchanger NHE3 at PKA consensus sites
Am J Physiol Renal Physiol 289: F249-F258, 2005. First published February 1, 2005; doi:10.1152/ajprenal.00082.2004 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Seema Basi, Lara B. Pupim, Edith M. Simmons, M. Tugrul Sezer, Yu Shyr, Stephanie Freedman, Glenn M. Chertow, Ravindra L. Mehta, Emil Paganini, Jonathan Himmelfarb, T. Alp Ikizler, and Program to Improve Care in Acute Renal Disease Study Group

Insulin resistance in critically ill patients with acute renal failure
Am J Physiol Renal Physiol 289: F259-F264, 2005. First published April 19, 2005; doi:10.1152/ajprenal.00002.2005 [Abstract] [Full Text] [PDF]  

J. H. Robben, N. V. A. M. Knoers, and P. M. T. Deen

Characterization of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus in a polarized cell model
Am J Physiol Renal Physiol 289: F265-F272, 2005; doi:10.1152/ajprenal.00404.2004 [Abstract] [Full Text] [PDF]  

INVITED REVIEWS:

Christos Chatziantoniou and Jean-Claude Dussaule

Insights into the mechanisms of renal fibrosis: is it possible to achieve regression?
Am J Physiol Renal Physiol 289: F227-F234, 2005; doi:10.1152/ajprenal.00453.2004 [Abstract] [Full Text] [PDF]  

Rania Nasrallah and Richard L. Hébert

Prostacyclin signaling in the kidney: implications for health and disease
Am J Physiol Renal Physiol 289: F235-F246, 2005; doi:10.1152/ajprenal.00454.2004 [Abstract] [Full Text] [PDF]  

ARTICLES:

Hayley Dickinson, David W. Walker, Luise Cullen-McEwen, E. Marelyn Wintour, and Karen Moritz

The spiny mouse (Acomys cahirinus) completes nephrogenesis before birth
Am J Physiol Renal Physiol 289: F273-F279, 2005. First published March 1, 2005; doi:10.1152/ajprenal.00400.2004 [Abstract] [Full Text] [PDF]  

Marisa D. Covington, Kayla J. Bayless, Robert C. Burghardt, George E. Davis, and Alan R. Parrish

Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases
Am J Physiol Renal Physiol 289: F280-F288, 2005. First published March 15, 2005; doi:10.1152/ajprenal.00351.2004 [Abstract] [Full Text] [PDF]  

R. A. Zager, Ali C. M. Johnson, Sherry Y. Hanson, and Steve Lund

Ischemic proximal tubular injury primes mice to endotoxin-induced TNF- generation and systemic release
Am J Physiol Renal Physiol 289: F289-F297, 2005. First published March 29, 2005; doi:10.1152/ajprenal.00023.2005 [Abstract] [Full Text] [PDF]  

Meghna Trivedi and Mustafa F. Lokhandwala

Rosiglitazone restores renal D_1A receptor-G_s protein coupling by reducing receptor hyperphosphorylation in obese rats
Am J Physiol Renal Physiol 289: F298-F304, 2005. First published March 29, 2005; doi:10.1152/ajprenal.00362.2004 [Abstract] [Full Text] [PDF]  

Isam Abu-Amarah, Anil K. Bidani, Rifat Hacioglu, Geoffrey A. Williamson, and Karen A. Griffin

Differential effects of salt on renal hemodynamics and potential pressure transmission in stroke-prone and stroke-resistant spontaneously hypertensive rats
Am J Physiol Renal Physiol 289: F305-F313, 2005. First published April 12, 2005; doi:10.1152/ajprenal.00349.2004 [Abstract] [Full Text] [PDF]  

Wei-Zhong Ying and Paul W. Sanders

Enhanced expression of EGF receptor in a model of salt-sensitive hypertension
Am J Physiol Renal Physiol 289: F314-F321, 2005. First published April 12, 2005; doi:10.1152/ajprenal.00003.2005 [Abstract] [Full Text] [PDF]  

Rikke Nørregaard, Boye L. Jensen, Chunling Li, Weidong Wang, Mark A. Knepper, Søren Nielsen, and Jørgen Frøkiær

COX-2 inhibition prevents downregulation of key renal water and sodium transport proteins in response to bilateral ureteral obstruction
Am J Physiol Renal Physiol 289: F322-F333, 2005. First published April 19, 2005; doi:10.1152/ajprenal.00061.2005 [Abstract] [Full Text] [PDF]  

Omar A. Itani, John B. Stokes, and Christie P. Thomas

Nedd4–2 isoforms differentially associate with ENaC and regulate its activity
Am J Physiol Renal Physiol 289: F334-F346, 2005. First published April 5, 2005; doi:10.1152/ajprenal.00394.2004 [Abstract] [Full Text] [PDF]  

Mary E. Handlogten, Seong-Pyo Hong, Connie M. Westhoff, and I. David Weiner

Apical ammonia transport by the mouse inner medullary collecting duct cell (mIMCD-3)
Am J Physiol Renal Physiol 289: F347-F358, 2005. First published March 29, 2005; doi:10.1152/ajprenal.00253.2004 [Abstract] [Full Text] [PDF]  

Stephanie Krämer, Tanja Loof, Sebastian Martini, Matthias Rückert, Yingrui Wang, Torsten Böhler, Fuijo Shimizu, Hiroshi Kawachi, Hans-H. Neumayer, and Harm Peters

Mycophenolate mofetil slows progression in anti-thy1-induced chronic renal fibrosis but is not additive to a high dose of enalapril
Am J Physiol Renal Physiol 289: F359-F368, 2005. First published March 15, 2005; doi:10.1152/ajprenal.00442.2004 [Abstract] [Full Text] [PDF]  

George Gallos, Thomas D. Ruyle, Charles W. Emala, and H. Thomas Lee

A₁ adenosine receptor knockout mice exhibit increased mortality, renal dysfunction, and hepatic injury in murine septic peritonitis
Am J Physiol Renal Physiol 289: F369-F376, 2005. First published March 22, 2005; doi:10.1152/ajprenal.00470.2004 [Abstract] [Full Text] [PDF]  

Xiaoming Zhou, Joan D. Ferraris, Qi Cai, Anupam Agarwal, and Maurice B. Burg

Increased reactive oxygen species contribute to high NaCl-induced activation of the osmoregulatory transcription factor TonEBP/OREBP
Am J Physiol Renal Physiol 289: F377-F385, 2005. First published March 15, 2005; doi:10.1152/ajprenal.00463.2004 [Abstract] [Full Text] [PDF]  

Elvira L. Liclican, John C. McGiff, Paulina L. Pedraza, Nicholas R. Ferreri, John R. Falck, and Mairead A. Carroll

Exaggerated response to adenosine in kidneys from high salt-fed rats: role of epoxyeicosatrienoic acids
Am J Physiol Renal Physiol 289: F386-F392, 2005. First published April 5, 2005; doi:10.1152/ajprenal.00421.2004 [Abstract] [Full Text] [PDF]  

Liliana Monica Bivol, Øyvind Brune Vågnes, and Bjarne Magnus Iversen

The renal vascular response to ANG II injection is reduced in the nonclipped kidney of two-kidney, one-clip hypertension
Am J Physiol Renal Physiol 289: F393-F400, 2005. First published March 22, 2005; doi:10.1152/ajprenal.00319.2004 [Abstract] [Full Text] [PDF]  

Christudas Morais, Justin Westhuyzen, Betty Pat, Glenda Gobe, and Helen Healy

High ambient glucose is effect neutral on cell death and proliferation in human proximal tubular epithelial cells
Am J Physiol Renal Physiol 289: F401-F409, 2005. First published April 12, 2005; doi:10.1152/ajprenal.00408.2004 [Abstract] [Full Text] [PDF]  

Craig Brooks, Pimonrat Ketsawatsomkron, Yang Sui, Jinzhao Wang, Cong-Yi Wang, Fu-Shin Yu, and Zheng Dong

Acidic pH inhibits ATP depletion-induced tubular cell apoptosis by blocking caspase-9 activation in apoptosome
Am J Physiol Renal Physiol 289: F410-F419, 2005. First published March 8, 2005; doi:10.1152/ajprenal.00440.2004 [Abstract] [Full Text] [PDF]  

Mariana G. Rosca, Tiberiu G. Mustata, Michael T. Kinter, Aylin M. Ozdemir, Timothy S. Kern, Luke I. Szweda, Michael Brownlee, Vincent M. Monnier, and Miriam F. Weiss

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation
Am J Physiol Renal Physiol 289: F420-F430, 2005. First published April 5, 2005; doi:10.1152/ajprenal.00415.2004 [Abstract] [Full Text] [PDF]  

Maribel Rico, Amitava Mukherjee, Martha Konieczkowski, Leslie A. Bruggeman, R. Tyler Miller, Shenaz Khan, Jeffrey R. Schelling, and John R. Sedor

WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment
Am J Physiol Renal Physiol 289: F431-F441, 2005. First published March 29, 2005; doi:10.1152/ajprenal.00389.2004 [Abstract] [Full Text] [PDF]  

Osman Khan, Shahla Riazi, Xinqun Hu, Jian Song, James B. Wade, and Carolyn A. Ecelbarger

Regulation of the renal thiazide-sensitive Na-Cl cotransporter, blood pressure, and natriuresis in obese Zucker rats treated with rosiglitazone
Am J Physiol Renal Physiol 289: F442-F450, 2005. First published April 5, 2005; doi:10.1152/ajprenal.00335.2004 [Abstract] [Full Text] [PDF]  

Hideki Inoue, Shelley D. Kozlowski, Janet D. Klein, James L. Bailey, Jeff M. Sands, and Serena M. Bagnasco

Regulated expression of renal and intestinal UT-B urea transporter in response to varying urea load
Am J Physiol Renal Physiol 289: F451-F458, 2005. First published March 29, 2005; doi:10.1152/ajprenal.00376.2004 [Abstract] [Full Text] [PDF]  

W. R. Cross, I. Eardley, H. J. Leese, and J. Southgate

A biomimetic tissue from cultured normal human urothelial cells: analysis of physiological function
Am J Physiol Renal Physiol 289: F459-F468, 2005. First published March 22, 2005; doi:10.1152/ajprenal.00040.2005 [Abstract] [Full Text] [PDF]  

Shenyang Li, Neriman Gokden, Mark D. Okusa, Renu Bhatt, and Didier Portilla

Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF
Am J Physiol Renal Physiol 289: F469-F480, 2005. First published April 5, 2005; doi:10.1152/ajprenal.00038.2005 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGIES:

Marcus J. Moeller, Abdulsalam Soofi, Silja Sanden, Jürgen Floege, Wilhelm Kriz, and Lawrence B. Holzman

An efficient system for tissue-specific overexpression of transgenes in podocytes in vivo
Am J Physiol Renal Physiol 289: F481-F488, 2005. First published March 22, 2005; doi:10.1152/ajprenal.00332.2004 [Abstract] [Full Text] [PDF]  

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