AJP - Renal Physiology -- Table of Contents (July 1 2007, 293 [1])

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EDITORIAL:

Thomas R. Kleyman: Renal physiology: an evolving field
Am J Physiol Renal Physiol 293: F1-F1, 2007. First published April 25, 2007; doi:10.1152/ajprenal.00189.2007 [Full Text] [PDF]

EDITORIAL FOCUS:

Dominic Cosgrove: A complex, tissue-specific role for plasmin and its regulators in modulating fibrogenic activity
Am J Physiol Renal Physiol 293: F10-F11, 2007. First published May 9, 2007; doi:10.1152/ajprenal.00143.2007 [Full Text] [PDF]

Ikuyo Yamaguchi, Jesus M. Lopez-Guisa, Xiaohe Cai, Sarah J. Collins, Daryl M. Okamura, and Allison A. Eddy: Endogenous urokinase lacks antifibrotic activity during progressive renal injury
Am J Physiol Renal Physiol 293: F12-F19, 2007. First published March 13, 2007; doi:10.1152/ajprenal.00380.2006 [Abstract] [Full Text] [PDF]

Douglas H. Sweet: Kinase signaling pathways regulate fine tuning of transporter activity
Am J Physiol Renal Physiol 293: F20-F20, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00126.2007 [Full Text] [PDF]

Sunhapas Soodvilai, Atip Chatsudthipong, and Varanuj Chatsudthipong: Role of MAPK and PKA in regulation of rbOCT2-mediated renal organic cation transport
Am J Physiol Renal Physiol 293: F21-F27, 2007. First published February 27, 2007; doi:10.1152/ajprenal.00043.2007 [Abstract] [Full Text] [PDF]

Alaa S. Awad and Mark D. Okusa: Distant organ injury following acute kidney injury
Am J Physiol Renal Physiol 293: F28-F29, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00159.2007 [Full Text] [PDF]

Heitham T. Hassoun, Dmitry N. Grigoryev, Mihaela L. Lie, Manchang Liu, Chris Cheadle, Rubin M. Tuder, and Hamid Rabb: Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy
Am J Physiol Renal Physiol 293: F30-F40, 2007. First published February 27, 2007; doi:10.1152/ajprenal.00023.2007 [Abstract] [Full Text] [PDF]

Subhashini Bolisetty and Anupam Agarwal: Subclinical kidney injury incites endotoxin hyperresponsiveness
Am J Physiol Renal Physiol 293: F41-F42, 2007. First published May 16, 2007; doi:10.1152/ajprenal.00224.2007 [Full Text] [PDF]

Richard A. Zager: "Subclinical" gentamicin nephrotoxicity: a potential risk factor for exaggerated endotoxin-driven TNF- ${alpha}$ production
Am J Physiol Renal Physiol 293: F43-F49, 2007. First published April 18, 2007; doi:10.1152/ajprenal.00144.2007 [Abstract] [Full Text] [PDF]

Michael S. Goligorsky: How to keep kidneys safe while shrinking tumors: the conundrum of cisplatin action
Am J Physiol Renal Physiol 293: F50-F51, 2007. First published May 16, 2007; doi:10.1152/ajprenal.00218.2007 [Full Text] [PDF]

Fang Yu, Judit Megyesi, Robert L. Safirstein, and Peter M. Price: Involvement of the CDK2-E2F1 pathway in cisplatin cytotoxicity in vitro and in vivo
Am J Physiol Renal Physiol 293: F52-F59, 2007. First published April 25, 2007; doi:10.1152/ajprenal.00119.2007 [Abstract] [Full Text] [PDF]

INVITED REVIEWS:

Norma A. Bobadilla and Gerardo Gamba: New insights into the pathophysiology of cyclosporine nephrotoxicity: a role of aldosterone
Am J Physiol Renal Physiol 293: F2-F9, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00072.2007 [Abstract] [Full Text] [PDF]

ARTICLES:

Sungmi Park, Benjamin J. Bivona, and Lisa M. Harrison-Bernard: Compromised renal microvascular reactivity of angiotensin type 1 double null mice
Am J Physiol Renal Physiol 293: F60-F67, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00049.2007 [Abstract] [Full Text] [PDF]

Clint Perry, Hong Le, and Irina I. Grichtchenko: ANG II and calmodulin/CaMKII regulate surface expression and functional activity of NBCe1 via separate means
Am J Physiol Renal Physiol 293: F68-F77, 2007. First published March 20, 2007; doi:10.1152/ajprenal.00454.2006 [Abstract] [Full Text] [PDF]

Juan M. Mejía-Vilet, Victoria Ramírez, Cristino Cruz, Norma Uribe, Gerardo Gamba, and Norma A. Bobadilla: Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone
Am J Physiol Renal Physiol 293: F78-F86, 2007. First published March 20, 2007; doi:10.1152/ajprenal.00077.2007 [Abstract] [Full Text] [PDF]

Sophie de Seigneux, Jakob Nielsen, Emma T. B. Olesen, Henrik Dimke, Tae-Hwan Kwon, Jørgen Frøkiær, and Søren Nielsen: Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidney
Am J Physiol Renal Physiol 293: F87-F99, 2007. First published March 20, 2007; doi:10.1152/ajprenal.00431.2006 [Abstract] [Full Text] [PDF]

Yuri Ozawa and Hiroyuki Kobori: Crucial role of Rho-nuclear factor- ${kappa}$ B axis in angiotensin II-induced renal injury
Am J Physiol Renal Physiol 293: F100-F109, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00520.2006 [Abstract] [Full Text] [PDF]

Yuehan Zhou, Patrice Bouyer, and Walter F. Boron: Role of the AT_1A receptor in the CO₂-induced stimulation of HCO₃^– reabsorption by renal proximal tubules
Am J Physiol Renal Physiol 293: F110-F120, 2007. First published March 13, 2007; doi:10.1152/ajprenal.00516.2006 [Abstract] [Full Text] [PDF]

Di Zhao, Elangovan Vellaichamy, Naveen K. Somanna, and Kailash N. Pandey: Guanylyl cyclase/natriuretic peptide receptor-A gene disruption causes increased adrenal angiotensin II and aldosterone levels
Am J Physiol Renal Physiol 293: F121-F127, 2007. First published March 27, 2007; doi:10.1152/ajprenal.00478.2006 [Abstract] [Full Text] [PDF]

Akiyuki Taruno, Naomi Niisato, and Yoshinori Marunaka: Hypotonicity stimulates renal epithelial sodium transport by activating JNK via receptor tyrosine kinases
Am J Physiol Renal Physiol 293: F128-F138, 2007. First published March 6, 2007; doi:10.1152/ajprenal.00011.2007 [Abstract] [Full Text] [PDF]

Rudy M. Ortiz, Miguel L. Graciano, Dale Seth, Mouhamed S. Awayda, and L. Gabriel Navar: Aldosterone receptor antagonism exacerbates intrarenal angiotensin II augmentation in ANG II-dependent hypertension
Am J Physiol Renal Physiol 293: F139-F147, 2007. First published March 20, 2007; doi:10.1152/ajprenal.00504.2006 [Abstract] [Full Text] [PDF]

Hui Zhang, Andrey V. Cybulsky, Lamine Aoudjit, Jianxin Zhu, Hongping Li, Nathalie Lamarche-Vane, and Tomoko Takano: Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury
Am J Physiol Renal Physiol 293: F148-F156, 2007. First published March 20, 2007; doi:10.1152/ajprenal.00294.2006 [Abstract] [Full Text] [PDF]

Laurinda A. Cooker, Darryl Peterson, Joann Rambow, Melisa L. Riser, Rebecca E. Riser, Feridoon Najmabadi, David Brigstock, and Bruce L. Riser: TNF- ${alpha}$ , but not IFN- ${gamma}$ , regulates CCN2 (CTGF), collagen type I, and proliferation in mesangial cells: possible roles in the progression of renal fibrosis
Am J Physiol Renal Physiol 293: F157-F165, 2007. First published March 20, 2007; doi:10.1152/ajprenal.00508.2006 [Abstract] [Full Text] [PDF]

Susanne Angelow, Randa El-Husseini, Sanae A. Kanzawa, and Alan S. L. Yu: Renal localization and function of the tight junction protein, claudin-19
Am J Physiol Renal Physiol 293: F166-F177, 2007. First published March 27, 2007; doi:10.1152/ajprenal.00087.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Swasti Tiwari, Lina Nordquist, Veerendra K. Madala Halagappa, and Carolyn A. Ecelbarger: Trafficking of ENaC subunits in response to acute insulin in mouse kidney
Am J Physiol Renal Physiol 293: F178-F185, 2007. First published March 27, 2007; doi:10.1152/ajprenal.00447.2006 [Abstract] [Full Text] [PDF]

Kristie Usa, Ravinder J. Singh, Brian C. Netzel, Yong Liu, Hershel Raff, and Mingyu Liang: Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats
Am J Physiol Renal Physiol 293: F186-F192, 2007. First published March 27, 2007; doi:10.1152/ajprenal.00484.2006 [Abstract] [Full Text] [PDF]

Maggie Keck, Melissa J. Romero-Aleshire, Qi Cai, Patricia B. Hoyer, and Heddwen L. Brooks: Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause
Am J Physiol Renal Physiol 293: F193-F199, 2007. First published March 27, 2007; doi:10.1152/ajprenal.00022.2007 [Abstract] [Full Text] [PDF] [Supplemental Table]

Vijaya L. Damaraju, Adam N. Elwi, Charlene Hunter, Pat Carpenter, Cheryl Santos, Gerry M. Barron, Xuejun Sun, Stephen A. Baldwin, James D. Young, John R. Mackey, Michael B. Sawyer, and Carol E. Cass: Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney
Am J Physiol Renal Physiol 293: F200-F211, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00007.2007 [Abstract] [Full Text] [PDF]

Hetal S. Kocinsky, Diane W. Dynia, Tong Wang, and Peter S. Aronson: NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity
Am J Physiol Renal Physiol 293: F212-F218, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00042.2007 [Abstract] [Full Text] [PDF]

Shougang Zhuang, Yan Yan, Rebecca A. Daubert, and Rick G. Schnellmann: Epiregulin promotes proliferation and migration of renal proximal tubular cells
Am J Physiol Renal Physiol 293: F219-F226, 2007. First published March 27, 2007; doi:10.1152/ajprenal.00082.2007 [Abstract] [Full Text] [PDF]

Wen Liu, Tetsuji Morimoto, Craig Woda, Thomas R. Kleyman, and Lisa M. Satlin: Ca²⁺ dependence of flow-stimulated K secretion in the mammalian cortical collecting duct
Am J Physiol Renal Physiol 293: F227-F235, 2007. First published March 27, 2007; doi:10.1152/ajprenal.00057.2007 [Abstract] [Full Text] [PDF]

Ling Yu, Douglas C. Eaton, and My N. Helms: Effect of divalent heavy metals on epithelial Na⁺ channels in A6 cells
Am J Physiol Renal Physiol 293: F236-F244, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00002.2007 [Abstract] [Full Text] [PDF]

Akanksha Gupta, George J. Rhodes, David T. Berg, Bruce Gerlitz, Bruce A. Molitoris, and Brian W. Grinnell: Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2
Am J Physiol Renal Physiol 293: F245-F254, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00477.2006 [Abstract] [Full Text] [PDF]

Amy M. Becker, Jianning Zhang, Sunita Goyal, Vangipuram Dwarakanath, Peter S. Aronson, Orson W. Moe, and Michel Baum: Ontogeny of NHE8 in the rat proximal tubule
Am J Physiol Renal Physiol 293: F255-F261, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00400.2006 [Abstract] [Full Text] [PDF]

Christopher M. Coleman, Jordan J. Minor, Laura E. Burt, Barbara A. Thornhill, Michael S. Forbes, and Robert L. Chevalier: Angiotensin AT₁-receptor inhibition exacerbates renal injury resulting from partial unilateral ureteral obstruction in the neonatal rat
Am J Physiol Renal Physiol 293: F262-F268, 2007. First published April 18, 2007; doi:10.1152/ajprenal.00071.2007 [Abstract] [Full Text] [PDF]

Kimberly R. Spurgeon-Pechman, Deborah L. Donohoe, David L. Mattson, Hayley Lund, Leilani James, and David P. Basile: Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium
Am J Physiol Renal Physiol 293: F269-F278, 2007. First published May 16, 2007; doi:10.1152/ajprenal.00279.2006 [Abstract] [Full Text] [PDF]

Mona Oppermann, Pernille B. Hansen, Hayo Castrop, and Jurgen Schnermann: Vasodilatation of afferent arterioles and paradoxical increase of renal vascular resistance by furosemide in mice
Am J Physiol Renal Physiol 293: F279-F287, 2007. First published May 9, 2007; doi:10.1152/ajprenal.00073.2007 [Abstract] [Full Text] [PDF]

Rolf M. Nüsing, Horst Schweer, Ingrid Fleming, Darryl C. Zeldin, and Markus Wegmann: Epoxyeicosatrienoic acids affect electrolyte transport in renal tubular epithelial cells: dependence on cyclooxygenase and cell polarity
Am J Physiol Renal Physiol 293: F288-F298, 2007. First published May 9, 2007; doi:10.1152/ajprenal.00171.2006 [Abstract] [Full Text] [PDF]

Ruimin Gu, Jing Wang, Yunhong Zhang, Wennan Li, Ying Xu, Hongli Shan, Wen-Hui Wang, and Baofeng Yang: Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney
Am J Physiol Renal Physiol 293: F299-F305, 2007. First published May 2, 2007; doi:10.1152/ajprenal.00008.2007 [Abstract] [Full Text] [PDF]

Anees Ahmad Banday and Mustafa F. Lokhandwala: Oxidative stress reduces renal dopamine D1 receptor-G_q/11 ${alpha}$ G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2
Am J Physiol Renal Physiol 293: F306-F315, 2007. First published April 25, 2007; doi:10.1152/ajprenal.00108.2007 [Abstract] [Full Text] [PDF]

Marcelo D. Carattino, Wen Liu, Warren G. Hill, Lisa M. Satlin, and Thomas R. Kleyman: Lack of a role of membrane-protein interactions in flow-dependent activation of ENaC
Am J Physiol Renal Physiol 293: F316-F324, 2007. First published April 25, 2007; doi:10.1152/ajprenal.00455.2006 [Abstract] [Full Text] [PDF]

Ganesan Ramesh, Binzhi Zhang, Satoshi Uematsu, Shizuo Akira, and W. Brian Reeves: Endotoxin and cisplatin synergistically induce renal dysfunction and cytokine production in mice
Am J Physiol Renal Physiol 293: F325-F332, 2007. First published May 9, 2007; doi:10.1152/ajprenal.00158.2007 [Abstract] [Full Text] [PDF]

Chunling Li, Weidong Wang, Rikke Norregaard, Mark A. Knepper, Søren Nielsen, and Jørgen Frøkiær: Altered expression of epithelial sodium channel in rats with bilateral or unilateral ureteral obstruction
Am J Physiol Renal Physiol 293: F333-F341, 2007. First published May 2, 2007; doi:10.1152/ajprenal.00372.2006 [Abstract] [Full Text] [PDF]

Hui Huang, Christophe Morisseau, JingFeng Wang, Tianxin Yang, John R. Falck, Bruce D. Hammock, and Mong-Heng Wang: Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats
Am J Physiol Renal Physiol 293: F342-F349, 2007. First published April 18, 2007; doi:10.1152/ajprenal.00004.2007 [Abstract] [Full Text] [PDF]

P. Richard Grimm, Ruth M. Foutz, Robert Brenner, and Steven C. Sansom: Identification and localization of BK- $beta$ subunits in the distal nephron of the mouse kidney
Am J Physiol Renal Physiol 293: F350-F359, 2007. First published April 25, 2007; doi:10.1152/ajprenal.00018.2007 [Abstract] [Full Text] [PDF]

Xiaohong Zhang, Nathan J. Cherrington, and Stephen H. Wright: Molecular identification and functional characterization of rabbit MATE1 and MATE2-K
Am J Physiol Renal Physiol 293: F360-F370, 2007. First published April 18, 2007; doi:10.1152/ajprenal.00102.2007 [Abstract] [Full Text] [PDF]

Elena Daghini, Xiang-Yang Zhu, Daniele Versari, Michael D. Bentley, Claudio Napoli, Amir Lerman, and Lilach O. Lerman: Antioxidant vitamins induce angiogenesis in the normal pig kidney
Am J Physiol Renal Physiol 293: F371-F381, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00475.2006 [Abstract] [Full Text] [PDF]

Alexander W. Krug, Katharina Völker, William H. Dantzler, and Stefan Silbernagl: Why is D-serine nephrotoxic and ${alpha}$ -aminoisobutyric acid protective?
Am J Physiol Renal Physiol 293: F382-F390, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00441.2006 [Abstract] [Full Text] [PDF]

Harumasa Ueo, Hideyuki Motohashi, Toshiya Katsura, and Ken-ichi Inui: Cl^–-dependent upregulation of human organic anion transporters: different effects on transport kinetics between hOAT1 and hOAT3
Am J Physiol Renal Physiol 293: F391-F397, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00376.2006 [Abstract] [Full Text] [PDF]

Juan Carlos Q. Velez, Alison M. Bland, John M. Arthur, John R. Raymond, and Michael G. Janech: Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes
Am J Physiol Renal Physiol 293: F398-F407, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00050.2007 [Abstract] [Full Text] [PDF]

Un Sil Jeon, Ki-Hwan Han, Soo-Hyun Park, Sang Do Lee, Mee Rie Sheen, Ju-Young Jung, Wan Young Kim, Jeff M. Sands, Jin Kim, and H. Moo Kwon: Downregulation of renal TonEBP in hypokalemic rats
Am J Physiol Renal Physiol 293: F408-F415, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00502.2006 [Abstract] [Full Text] [PDF]

Nilufar Mohebbi, Jana Kovacikova, Marta Nowik, and Carsten A. Wagner: Thyroid hormone deficiency alters expression of acid-base transporters in rat kidney
Am J Physiol Renal Physiol 293: F416-F427, 2007. First published April 4, 2007; doi:10.1152/ajprenal.00391.2006 [Abstract] [Full Text] [PDF]

INNOVATIVE METHODOLOGY:

Martin H. de Borst, Sander H. Diks, Juliane Bolbrinker, Mark W. Schellings, Mario B. A. van Dalen, Maikel P. Peppelenbosch, Reinhold Kreutz, Yigal M. Pinto, Gerjan Navis, and Harry van Goor: Profiling of the renal kinome: a novel tool to identify protein kinases involved in angiotensin II-dependent hypertensive renal damage
Am J Physiol Renal Physiol 293: F428-F437, 2007. First published April 11, 2007; doi:10.1152/ajprenal.00367.2006 [Abstract] [Full Text] [PDF]

LETTERS TO THE EDITOR:

Mordecai P. Blaustein, John M. Hamlyn, and Thomas L. Pallone: Sodium pumps: ouabain, ion transport, and signaling in hypertension
Am J Physiol Renal Physiol 293: F438-F438, 2007; doi:10.1152/ajprenal.00092.2007 [Full Text] [PDF]

Jonathan D. Kaunitz: Reply to Blaustein et al.
Am J Physiol Renal Physiol 293: F439-F439, 2007; doi:10.1152/ajprenal.00206.2007 [Full Text] [PDF]

Joel C. Geerling and Arthur D. Loewy: 11 $beta$ -Hydroxysteroid dehydrogenase 2 vs. transgene: discrepant loci of expression in the adult brain
Am J Physiol Renal Physiol 293: F440-F441, 2007; doi:10.1152/ajprenal.00517.2006 [Full Text] [PDF]

Anikó Náray-Fejes-Tóth and Géza Fejes-Tóth: Reply to Geerling and Loewy
Am J Physiol Renal Physiol 293: F442-F443, 2007; doi:10.1152/ajprenal.00211.2007 [Full Text] [PDF] [Corrected Link]

Cover Caption:

Cover

Cover: Immunohistochemical labeling of epithelial sodium channel ENaC in renal collecting duct principal cells. See related article by de Seigneux S, Nielsen J, Olesen ETB, Dimke H, Kwon T-H, Frøkiær J, and Nielsen S. Long-term aldosterone treatment induces decreased apical but increased basolateral expression of AQP2 in CCD of rat kidney. Am J Physiol Renal Physiol. 293: F87–F99, 2007.