EDITORIAL FOCUS:

Rebecca P. Hughey and Thomas R. Kleyman

Functional cross talk between ENaC and pendrin
Am J Physiol Renal Physiol 293: F1439-F1440, 2007. First published September 12, 2007; doi:10.1152/ajprenal.00402.2007 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Jane Goddard, Neil R. Johnston, Allan D. Cumming, and David J. Webb

Fractional urinary excretion of endothelin-1 is reduced by acute ETB receptor blockade
Am J Physiol Renal Physiol 293: F1433-F1438, 2007. First published September 12, 2007; doi:10.1152/ajprenal.00101.2007 [Abstract] [Full Text] [PDF]  

INVITED REVIEWS:

Thomas Weimbs

Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1
Am J Physiol Renal Physiol 293: F1423-F1432, 2007. First published August 22, 2007; doi:10.1152/ajprenal.00275.2007 [Abstract] [Full Text] [PDF]  

ARTICLES:

David A. Vesey, Wade A. Kruger, Philip Poronnik, Glenda C. Gobé, and David W. Johnson

Proinflammatory and proliferative responses of human proximal tubule cells to PAR-2 activation
Am J Physiol Renal Physiol 293: F1441-F1449, 2007. First published August 15, 2007; doi:10.1152/ajprenal.00088.2007 [Abstract] [Full Text] [PDF]  

G. Jacquillet, O. Barbier, I. Rubera, M. Tauc, A. Borderie, M. C. Namorado, D. Martin, G. Sierra, J. L. Reyes, P. Poujeol, and M. Cougnon

Cadmium causes delayed effects on renal function in the offspring of cadmium-contaminated pregnant female rats
Am J Physiol Renal Physiol 293: F1450-F1460, 2007. First published August 8, 2007; doi:10.1152/ajprenal.00223.2007 [Abstract] [Full Text] [PDF]  

R. Noronha, H. Akbarali, A. Malykhina, R. D. Foreman, and Beverley Greenwood-Van Meerveld

Changes in urinary bladder smooth muscle function in response to colonic inflammation
Am J Physiol Renal Physiol 293: F1461-F1467, 2007. First published August 22, 2007; doi:10.1152/ajprenal.00311.2007 [Abstract] [Full Text] [PDF]  

Jie Xu, Bing Yao, Xiaofeng Fan, Melissa M. Langworthy, Ming-Zhi Zhang, and Raymond C. Harris

Characterization of a putative intrarenal serotonergic system
Am J Physiol Renal Physiol 293: F1468-F1475, 2007. First published August 22, 2007; doi:10.1152/ajprenal.00246.2007 [Abstract] [Full Text] [PDF]  

Monu Goel, William G. Sinkins, Cheng-Di Zuo, Ulrich Hopfer, and William P. Schilling

Vasopressin-induced membrane trafficking of TRPC3 and AQP2 channels in cells of the rat renal collecting duct
Am J Physiol Renal Physiol 293: F1476-F1488, 2007. First published August 15, 2007; doi:10.1152/ajprenal.00186.2007 [Abstract] [Full Text] [PDF]  

Armin Just and William J. Arendshorst

A novel mechanism of renal blood flow autoregulation and the autoregulatory role of A₁ adenosine receptors in mice
Am J Physiol Renal Physiol 293: F1489-F1500, 2007. First published August 29, 2007; doi:10.1152/ajprenal.00256.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

Almut Grenz, Hua Zhang, Jochen Weingart, Simone von Wietersheim, Tobias Eckle, Juergen Schnermann, Christoph Köhle, Doris Kloor, Christoph H. Gleiter, Volker Vallon, Holger K. Eltzschig, and Hartmut Osswald

Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia
Am J Physiol Renal Physiol 293: F1501-F1511, 2007. First published September 12, 2007; doi:10.1152/ajprenal.00243.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

Haikun Shi, Daniel Patschan, Tracy Epstein, Michael S. Goligorsky, and Joseph Winaver

Delayed recovery of renal regional blood flow in diabetic mice subjected to acute ischemic kidney injury
Am J Physiol Renal Physiol 293: F1512-F1517, 2007. First published September 19, 2007; doi:10.1152/ajprenal.00215.2007 [Abstract] [Full Text] [PDF]  

Aurélie Edwards and Thomas L. Pallone

Ouabain modulation of cellular calcium stores and signaling
Am J Physiol Renal Physiol 293: F1518-F1532, 2007. First published August 1, 2007; doi:10.1152/ajprenal.00251.2007 [Abstract] [Full Text] [PDF]  

Catarina Rippe, Anna Rippe, Ole Torffvit, and Bengt Rippe

Size and charge selectivity of the glomerular filter in early experimental diabetes in rats
Am J Physiol Renal Physiol 293: F1533-F1538, 2007. First published August 15, 2007; doi:10.1152/ajprenal.00271.2007 [Abstract] [Full Text] [PDF]  

D. Z. I. Cherney, J. W. Scholey, D. C. Cattran, A. K. Kang, J. Zimpelmann, C. Kennedy, V. Lai, K. D. Burns, and J. A. Miller

The effect of oral contraceptives on the nitric oxide system and renal function
Am J Physiol Renal Physiol 293: F1539-F1544, 2007. First published August 22, 2007; doi:10.1152/ajprenal.00351.2007 [Abstract] [Full Text] [PDF]  

Olga V. Sosnovtseva, Alexey N. Pavlov, Erik Mosekilde, Kay-Pong Yip, Niels-Henrik Holstein-Rathlou, and Donald J. Marsh

Synchronization among mechanisms of renal autoregulation is reduced in hypertensive rats
Am J Physiol Renal Physiol 293: F1545-F1555, 2007. First published August 29, 2007; doi:10.1152/ajprenal.00054.2007 [Abstract] [Full Text] [PDF]  

Frank Y. Ma, Greg H. Tesch, Richard A. Flavell, Roger J. Davis, and David J. Nikolic-Paterson

MKK3-p38 signaling promotes apoptosis and the early inflammatory response in the obstructed mouse kidney
Am J Physiol Renal Physiol 293: F1556-F1563, 2007. First published August 8, 2007; doi:10.1152/ajprenal.00010.2007 [Abstract] [Full Text] [PDF]  

Moto Kajiwara, Tomohiro Terada, Jun-ichi Asaka, Ken Ogasawara, Toshiya Katsura, Osamu Ogawa, Atsushi Fukatsu, Toshio Doi, and Ken-ichi Inui

Critical roles of Sp1 in gene expression of human and rat H⁺/organic cation antiporter MATE1
Am J Physiol Renal Physiol 293: F1564-F1570, 2007. First published September 12, 2007; doi:10.1152/ajprenal.00322.2007 [Abstract] [Full Text] [PDF]  

Sunhapas Soodvilai, Zhanjun Jia, and Tianxin Yang

Hydrogen peroxide stimulates chloride secretion in primary inner medullary collecting duct cells via mPGES-1-derived PGE₂
Am J Physiol Renal Physiol 293: F1571-F1576, 2007. First published August 15, 2007; doi:10.1152/ajprenal.00132.2007 [Abstract] [Full Text] [PDF]  

Farzana Perwad, Martin Y. H. Zhang, Harriet S. Tenenhouse, and Anthony A. Portale

Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1-hydroxylase expression in vitro
Am J Physiol Renal Physiol 293: F1577-F1583, 2007. First published August 15, 2007; doi:10.1152/ajprenal.00463.2006 [Abstract] [Full Text] [PDF]  

Rudy M. Ortiz, Miguel L. Graciano, John J. Mullins, and Kenneth D. Mitchell

Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats
Am J Physiol Renal Physiol 293: F1584-F1591, 2007. First published August 22, 2007; doi:10.1152/ajprenal.00124.2007 [Abstract] [Full Text] [PDF]  

J. Ruth Wu-Wong, Masaki Nakane, Junli Ma, Xiaoan Ruan, and Paul E. Kroeger

Elevated phosphorus modulates vitamin D receptor-mediated gene expression in human vascular smooth muscle cells
Am J Physiol Renal Physiol 293: F1592-F1604, 2007. First published August 22, 2007; doi:10.1152/ajprenal.00492.2006 [Abstract] [Full Text] [PDF]  

Karen A. Griffin, Mohammad Abu-Naser, Isam Abu-Amarah, Maria Picken, Geoffrey A. Williamson, and Anil K. Bidani

Dynamic blood pressure load and nephropathy in the ZSF1 (fa/fa^cp) model of type 2 diabetes
Am J Physiol Renal Physiol 293: F1605-F1613, 2007. First published August 29, 2007; doi:10.1152/ajprenal.00511.2006 [Abstract] [Full Text] [PDF]  

Margot S. Damaser, Mary K. Samplaski, Mansi Parikh, Dan Li Lin, Soujanya Rao, and James M. Kerns

Time course of neuroanatomical and functional recovery after bilateral pudendal nerve injury in female rats
Am J Physiol Renal Physiol 293: F1614-F1621, 2007. First published August 29, 2007; doi:10.1152/ajprenal.00176.2007 [Abstract] [Full Text] [PDF]  

Gerard Elberg, Dorit Elberg, Teresa V. Lewis, Suresh Guruswamy, Lijuan Chen, Charlotte J. Logan, Michael D. Chan, and Martin A. Turman

EP₂ receptor mediates PGE₂-induced cystogenesis of human renal epithelial cells
Am J Physiol Renal Physiol 293: F1622-F1632, 2007. First published August 29, 2007; doi:10.1152/ajprenal.00036.2007 [Abstract] [Full Text] [PDF]  

Kathleen D. Liu, Anirban Datta, Wei Yu, Paul R. Brakeman, Tzuu-Shuh Jou, Michael A. Matthay, and Keith E. Mostov

Rac1 is required for reorientation of polarity and lumen formation through a PI 3-kinase-dependent pathway
Am J Physiol Renal Physiol 293: F1633-F1640, 2007. First published September 5, 2007; doi:10.1152/ajprenal.00053.2007 [Abstract] [Full Text] [PDF]  

Grace M. Mitu, Shinong Wang, and Raimund Hirschberg

BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury
Am J Physiol Renal Physiol 293: F1641-F1648, 2007. First published September 5, 2007; doi:10.1152/ajprenal.00179.2007 [Abstract] [Full Text] [PDF]  

Susan Sheehan, Shirng-Wern Tsaih, Benjamin L. King, Caitlin Stanton, Gary A. Churchill, Beverly Paigen, and Keith DiPetrillo

Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice
Am J Physiol Renal Physiol 293: F1649-F1656, 2007. First published September 5, 2007; doi:10.1152/ajprenal.00233.2007 [Abstract] [Full Text] [PDF]  

Amy Wang, Fuad N. Ziyadeh, Eun Young Lee, Petr E. Pyagay, Sun Hee Sung, Steven A. Sheardown, Nicholas J. Laping, and Sheldon Chen

Interference with TGF- signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria
Am J Physiol Renal Physiol 293: F1657-F1665, 2007. First published September 5, 2007; doi:10.1152/ajprenal.00274.2007 [Abstract] [Full Text] [PDF]  

Ling Yu, Hui-Fang Bao, Julie L. Self, Douglas C. Eaton, and My N. Helms

Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells
Am J Physiol Renal Physiol 293: F1666-F1677, 2007. First published September 5, 2007; doi:10.1152/ajprenal.00444.2006 [Abstract] [Full Text] [PDF]  

Alexis Dixon and Christine Maric

17-Estradiol attenuates diabetic kidney disease by regulating extracellular matrix and transforming growth factor- protein expression and signaling
Am J Physiol Renal Physiol 293: F1678-F1690, 2007. First published August 8, 2007; doi:10.1152/ajprenal.00079.2007 [Abstract] [Full Text] [PDF]  

Cristino Cruz, Ricardo Correa-Rotter, Dolores Javier Sánchez-González, Rogelio Hernández-Pando, Perla D. Maldonado, Claudia María Martínez-Martínez, Omar Noel Medina-Campos, Edilia Tapia, Diana Aguilar, Yolanda I. Chirino, and José Pedraza-Chaverri

Renoprotective and antihypertensive effects of S-allylcysteine in 5/6 nephrectomized rats
Am J Physiol Renal Physiol 293: F1691-F1698, 2007. First published August 8, 2007; doi:10.1152/ajprenal.00235.2007 [Abstract] [Full Text] [PDF]  

Ling Wu, Xiaochong Gao, Rachel C. Brown, Stefan Heller, and Roger G. O'Neil

Dual role of the TRPV4 channel as a sensor of flow and osmolality in renal epithelial cells
Am J Physiol Renal Physiol 293: F1699-F1713, 2007. First published August 15, 2007; doi:10.1152/ajprenal.00462.2006 [Abstract] [Full Text] [PDF]  

Verena Pollack, Rita Sarközi, Zoltan Banki, Elisabeth Feifel, Swantje Wehn, Gerhard Gstraunthaler, Heribert Stoiber, Gert Mayer, Roberto Montesano, Frank Strutz, and Herbert Schramek

Oncostatin M-induced effects on EMT in human proximal tubular cells: differential role of ERK signaling
Am J Physiol Renal Physiol 293: F1714-F1726, 2007. First published September 19, 2007; doi:10.1152/ajprenal.00130.2007 [Abstract] [Full Text] [PDF]  

Shu Liu, Lihua Shi, and Shuxia Wang

Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury
Am J Physiol Renal Physiol 293: F1727-F1735, 2007. First published September 19, 2007; doi:10.1152/ajprenal.00316.2007 [Abstract] [Full Text] [PDF]  

Inga J. Murawski, David B. Myburgh, Jack Favor, and Indra R. Gupta

Vesico-ureteric reflux and urinary tract development in the Pax2^1Neu+/– mouse
Am J Physiol Renal Physiol 293: F1736-F1745, 2007. First published September 19, 2007; doi:10.1152/ajprenal.00221.2007 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Dirk M. Hentschel, Michael Mengel, Lisa Boehme, Fabian Liebsch, Caroline Albertin, Joseph V. Bonventre, Hermann Haller, and Mario Schiffer

Rapid screening of glomerular slit diaphragm integrity in larval zebrafish
Am J Physiol Renal Physiol 293: F1746-F1750, 2007. First published August 15, 2007; doi:10.1152/ajprenal.00009.2007 [Abstract] [Full Text] [PDF]  

REPORTS:

Liuzhe Li, Charles S. Wingo, and Shen-Ling Xia

Downregulation of SGK1 by nucleotides in renal tubular epithelial cells
Am J Physiol Renal Physiol 293: F1751-F1757, 2007. First published August 8, 2007; doi:10.1152/ajprenal.00091.2007 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Giovanni Gambaro and Cataldo Abaterusso

Pathophysiology of hypercalciuria
Am J Physiol Renal Physiol 293: F1758-F1758, 2007; doi:10.1152/ajprenal.00350.2007 [Full Text] [PDF]  

Daniel L. Gillen, Elaine M. Worcester, and Fredric L. Coe

Reply to Gambaro and Abaterusso
Am J Physiol Renal Physiol 293: F1759-F1759, 2007; doi:10.1152/ajprenal.00376.2007 [Full Text] [PDF]  

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