EDITORIAL FOCUS:

Michael B. Butterworth and John P. Johnson

USP10: the nexus between nexin and vasopressin
Am J Physiol Renal Physiol 295: F888-F888, 2008. First published July 30, 2008; doi:10.1152/ajprenal.90434.2008 [Full Text] [PDF]  

Giovanni Li Volti, Luca Vanella, Diego Gazzolo, and Fabio Galvano

Carbon monoxide: vasoconstrictor or vasodilator? That's the question
Am J Physiol Renal Physiol 295: F901-F903, 2008. First published August 6, 2008; doi:10.1152/ajprenal.90441.2008 [Full Text] [PDF]  

Fady T. Botros, Minolfa C. Prieto-Carrasquero, Victoria L. Martin, and L. Gabriel Navar

Heme oxygenase induction attenuates afferent arteriolar autoregulatory responses
Am J Physiol Renal Physiol 295: F904-F911, 2008. First published July 16, 2008; doi:10.1152/ajprenal.90377.2008 [Abstract] [Full Text] [PDF]  

ARTICLES:

Gamika A. Prathapasinghe, Yaw L. Siow, Zhibin Xu, and Karmin O

Inhibition of cystathionine-β-synthase activity during renal ischemia-reperfusion: role of pH and nitric oxide
Am J Physiol Renal Physiol 295: F912-F922, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00040.2008 [Abstract] [Full Text] [PDF]  

Sung-Lang Chen, Yu-Hui Huang, Yu-Lin Kao, Gin-Den Chen, Chen-Li Cheng, Hsien-Yu Peng, Jiuan-Miaw Liao, Pei-Chen Huang, Shih-Jei Tsai, and Tzer-Bin Lin

Acute anal stretch inhibits NMDA-dependent pelvic-urethra reflex potentiation via spinal GABAergic inhibition in anesthetized rats
Am J Physiol Renal Physiol 295: F923-F931, 2008. First published July 16, 2008; doi:10.1152/ajprenal.90254.2008 [Abstract] [Full Text] [PDF]  

Zhu Zhou, Patricia Gengaro, Wei Wang, Xue-qing Wang, Chunling Li, Sarah Faubel, Christopher Rivard, and Robert W. Schrier

Role of NF-B and PI 3-kinase/Akt in TNF--induced cytotoxicity in microvascular endothelial cells
Am J Physiol Renal Physiol 295: F932-F941, 2008. First published July 16, 2008; doi:10.1152/ajprenal.00066.2008 [Abstract] [Full Text] [PDF]  

Haiying Liu, Zhunjun Jia, Sunhapas Soodvilai, Guangju Guan, Mong-Heng Wang, Zheng Dong, J. David Symons, and Tianxin Yang

Nitro-oleic acid protects the mouse kidney from ischemia and reperfusion injury
Am J Physiol Renal Physiol 295: F942-F949, 2008. First published August 27, 2008; doi:10.1152/ajprenal.90236.2008 [Abstract] [Full Text] [PDF]  

Ya Su, Katherine G. Blake-Palmer, Sara Sorrell, Babak Javid, Katherine Bowers, Aiwu Zhou, Simon H. Chang, Seema Qamar, and Fiona E. Karet

Human H⁺ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1
Am J Physiol Renal Physiol 295: F950-F958, 2008. First published July 16, 2008; doi:10.1152/ajprenal.90258.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]  

Moin A. Saleem, Jiri Zavadil, Maryse Bailly, Karen McGee, Ian R. Witherden, Hermann Pavenstadt, Hsianghao Hsu, Julia Sanday, Simon C. Satchell, Rachel Lennon, Lan Ni, Erwin P. Bottinger, Peter Mundel, and Peter W. Mathieson

The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells
Am J Physiol Renal Physiol 295: F959-F970, 2008. First published August 6, 2008; doi:10.1152/ajprenal.00559.2007 [Abstract] [Full Text] [PDF]  

Ángeles García-Pascual, María Sancho, Gonzalo Costa, and Domingo Triguero

Interstitial cells of Cajal in the urethra are cGMP-mediated targets of nitrergic neurotransmission
Am J Physiol Renal Physiol 295: F971-F983, 2008. First published July 16, 2008; doi:10.1152/ajprenal.90301.2008 [Abstract] [Full Text] [PDF]  

Xin Su, Lisa A. Leon, Charlene W. Wu, Dwight M. Morrow, Jon-Paul Jaworski, J. Paul Hieble, Erin S. R. Lashinger, Jian Jin, Richard M. Edwards, and Nicholas J. Laping

Modulation of bladder function by prostaglandin EP₃ receptors in the central nervous system
Am J Physiol Renal Physiol 295: F984-F994, 2008. First published July 16, 2008; doi:10.1152/ajprenal.90373.2008 [Abstract] [Full Text] [PDF]  

Cynthia M. Miracle, Timo Rieg, Hadi Mansoury, Volker Vallon, and Scott C. Thomson

Ornithine decarboxylase inhibitor eliminates hyperresponsiveness of the early diabetic proximal tubule to dietary salt
Am J Physiol Renal Physiol 295: F995-F1002, 2008. First published June 18, 2008; doi:10.1152/ajprenal.00491.2007 [Abstract] [Full Text] [PDF]  

Li E. Yang, Monica B. Sandberg, Argun D. Can, Kaarina Pihakaski-Maunsbach, and Alicia A. McDonough

Effects of dietary salt on renal Na⁺ transporter subcellular distribution, abundance, and phosphorylation status
Am J Physiol Renal Physiol 295: F1003-F1016, 2008. First published July 23, 2008; doi:10.1152/ajprenal.90235.2008 [Abstract] [Full Text] [PDF]  

Baoyuan Bi, Jiankan Guo, Arnaud Marlier, Shin Ru Lin, and Lloyd G. Cantley

Erythropoietin expands a stromal cell population that can mediate renoprotection
Am J Physiol Renal Physiol 295: F1017-F1022, 2008. First published July 23, 2008; doi:10.1152/ajprenal.90218.2008 [Abstract] [Full Text] [PDF]  

Kuniko Kimura, Masayuki Iwano, Debra F. Higgins, Yukinari Yamaguchi, Kimihiko Nakatani, Koji Harada, Atsushi Kubo, Yasuhiro Akai, Erinn B. Rankin, Eric G. Neilson, Volker H. Haase, and Yoshihiko Saito

Stable expression of HIF-1 in tubular epithelial cells promotes interstitial fibrosis
Am J Physiol Renal Physiol 295: F1023-F1029, 2008. First published July 30, 2008; doi:10.1152/ajprenal.90209.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Trairak Pisitkun, Vinitha Jacob, Stephen M. Schleicher, Chung-Lin Chou, Ming-Jiun Yu, and Mark A. Knepper

Akt and ERK1/2 pathways are components of the vasopressin signaling network in rat native IMCD
Am J Physiol Renal Physiol 295: F1030-F1043, 2008. First published July 30, 2008; doi:10.1152/ajprenal.90339.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]  

Victoria Ramírez, Juan M. Mejía-Vilet, Damián Hernández, Gerardo Gamba, and Norma A. Bobadilla

Radicicol, a heat shock protein 90 inhibitor, reduces glomerular filtration rate
Am J Physiol Renal Physiol 295: F1044-F1051, 2008. First published July 30, 2008; doi:10.1152/ajprenal.90278.2008 [Abstract] [Full Text] [PDF]  

Viatcheslav Nesterov, Anke Dahlmann, Marko Bertog, and Christoph Korbmacher

Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron
Am J Physiol Renal Physiol 295: F1052-F1062, 2008. First published July 23, 2008; doi:10.1152/ajprenal.00031.2008 [Abstract] [Full Text] [PDF]  

Vladislav Bugaj, Oleh Pochynyuk, Elena Mironova, Alain Vandewalle, Jorge L. Medina, and James D. Stockand

Regulation of the epithelial Na⁺ channel by endothelin-1 in rat collecting duct
Am J Physiol Renal Physiol 295: F1063-F1070, 2008. First published July 30, 2008; doi:10.1152/ajprenal.90321.2008 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

Hongyu Zhang, Jharna Saha, Jaeman Byun, MaryLee Schin, Matthew Lorenz, Robert T. Kennedy, Matthias Kretzler, Eva L. Feldman, Subramaniam Pennathur, and Frank C. Brosius, III

Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy
Am J Physiol Renal Physiol 295: F1071-F1081, 2008. First published July 30, 2008; doi:10.1152/ajprenal.90208.2008 [Abstract] [Full Text] [PDF]  

Huda Ismail Abdullah, Paulina L. Pedraza, John C. McGiff, and Nicholas R. Ferreri

Calcium-sensing receptor signaling pathways in medullary thick ascending limb cells mediate COX-2-derived PGE₂ production: functional significance
Am J Physiol Renal Physiol 295: F1082-F1089, 2008. First published August 6, 2008; doi:10.1152/ajprenal.90316.2008 [Abstract] [Full Text] [PDF]  

Guillermo B. Silva and Jeffrey L. Garvin

TRPV4 mediates hypotonicity-induced ATP release by the thick ascending limb
Am J Physiol Renal Physiol 295: F1090-F1095, 2008. First published August 6, 2008; doi:10.1152/ajprenal.90365.2008 [Abstract] [Full Text] [PDF]  

Helene Francois, Natalia Makhanova, Philip Ruiz, Jonathan Ellison, Lan Mao, Howard A. Rockman, and Thomas M. Coffman

A role for the thromboxane receptor in L-NAME hypertension
Am J Physiol Renal Physiol 295: F1096-F1102, 2008. First published August 6, 2008; doi:10.1152/ajprenal.00369.2007 [Abstract] [Full Text] [PDF]  

Pia Welker, Stephanie Krämer, David A. Groneberg, Hans H. Neumayer, Sebastian Bachmann, Kerstin Amann, and Harm Peters

Increased mast cell number in human hypertensive nephropathy
Am J Physiol Renal Physiol 295: F1103-F1109, 2008. First published August 6, 2008; doi:10.1152/ajprenal.00374.2007 [Abstract] [Full Text] [PDF]  

Farah Khan, Zuzana Spicarová, Sergey Zelenin, Ulla Holtbäck, Lena Scott, and Anita Aperia

Negative reciprocity between angiotensin II type 1 and dopamine D1 receptors in rat renal proximal tubule cells
Am J Physiol Renal Physiol 295: F1110-F1116, 2008. First published August 13, 2008; doi:10.1152/ajprenal.90336.2008 [Abstract] [Full Text] [PDF]  

Angel R. Cinelli, Riad Efendiev, and Carlos H. Pedemonte

Trafficking of Na-K-ATPase and dopamine receptor molecules induced by changes in intracellular sodium concentration of renal epithelial cells
Am J Physiol Renal Physiol 295: F1117-F1125, 2008. First published August 13, 2008; doi:10.1152/ajprenal.90317.2008 [Abstract] [Full Text] [PDF]  

Julia Thumfart, Susanne Jung, Salah Amasheh, Stephanie Krämer, Harm Peters, Kerstin Sommer, Jürg Biber, Heini Murer, Iwan Meij, Uwe Querfeld, Carsten A. Wagner, and Dominik Müller

Magnesium stimulates renal phosphate reabsorption
Am J Physiol Renal Physiol 295: F1126-F1133, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00353.2007 [Abstract] [Full Text] [PDF]  

Laura G. Sánchez-Lozada, Virgilia Soto, Edilia Tapia, Carmen Avila-Casado, Yuri Y. Sautin, Takahiko Nakagawa, Martha Franco, Bernardo Rodríguez-Iturbe, and Richard J. Johnson

Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia
Am J Physiol Renal Physiol 295: F1134-F1141, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00104.2008 [Abstract] [Full Text] [PDF]  

Fannie Darlot, Annie Artuso, Nicole Lautredou-Audouy, and Daniel Casellas

Topology of Schwann cells and sympathetic innervation along preglomerular vessels: a confocal microscopic study in protein S100B/EGFP transgenic mice
Am J Physiol Renal Physiol 295: F1142-F1148, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00599.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

Sean M. Brown, Lilia M. Bentcheva-Petkova, Lei Liu, Kiril L. Hristov, Muyan Chen, Whitney F. Kellett, Andrea L. Meredith, Richard W. Aldrich, Mark T. Nelson, and Georgi V. Petkov

β-Adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca²⁺-activated K⁺ channel
Am J Physiol Renal Physiol 295: F1149-F1157, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00440.2007 [Abstract] [Full Text] [PDF]  

Silvia Kelsen, Bijal J. Patel, Lawson B. Parker, Trinity Vera, John M. Rimoldi, Rama S. V. Gadepalli, Heather A. Drummond, and David E. Stec

Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells
Am J Physiol Renal Physiol 295: F1158-F1165, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00057.2008 [Abstract] [Full Text] [PDF]  

Charity L. Sauder, Erin E. Conboy, Stephanie A. Chin-Sang, and Chester A. Ray

Otolithic activation on visceral circulation in humans: effect of aging
Am J Physiol Renal Physiol 295: F1166-F1169, 2008. First published August 13, 2008; doi:10.1152/ajprenal.90408.2008 [Abstract] [Full Text] [PDF]  

Yuichiro Izumi, Yushi Nakayama, Hasiyet Memetimin, Takeaki Inoue, Yukimasa Kohda, Hiroshi Nonoguchi, and Kimio Tomita

Regulation of V2R transcription by hypertonicity and V1aR-V2R signal interaction
Am J Physiol Renal Physiol 295: F1170-F1176, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00119.2008 [Abstract] [Full Text] [PDF]  

Nicole Schliebe, Rainer Strotmann, Kathy Busse, Doreen Mitschke, Heike Biebermann, Lutz Schomburg, Josef Köhrle, Jörg Bär, Holger Römpler, Jürgen Wess, Torsten Schöneberg, and Katrin Sangkuhl

V2 vasopressin receptor deficiency causes changes in expression and function of renal and hypothalamic components involved in electrolyte and water homeostasis
Am J Physiol Renal Physiol 295: F1177-F1190, 2008. First published August 20, 2008; doi:10.1152/ajprenal.00465.2007 [Abstract] [Full Text] [PDF]  

Matthew S. Reifenberger, Krista L. Arnett, Craig Gatto, and Mark A. Milanick

The reactive nitrogen species peroxynitrite is a potent inhibitor of renal Na-K-ATPase activity
Am J Physiol Renal Physiol 295: F1191-F1198, 2008. First published August 13, 2008; doi:10.1152/ajprenal.90296.2008 [Abstract] [Full Text] [PDF]  

Pedro San-Cristobal, José Ponce-Coria, Norma Vázquez, Norma A. Bobadilla, and Gerardo Gamba

WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na⁺-Cl^– cotransporter
Am J Physiol Renal Physiol 295: F1199-F1206, 2008. First published August 13, 2008; doi:10.1152/ajprenal.90396.2008 [Abstract] [Full Text] [PDF] [Supplemental Figure]  

YiLin Ren, Martin A. D'Ambrosio, Hong Wang, Ruisheng Liu, Jeffrey L. Garvin, and Oscar A. Carretero

Heme oxygenase metabolites inhibit tubuloglomerular feedback (TGF)
Am J Physiol Renal Physiol 295: F1207-F1212, 2008. First published August 20, 2008; doi:10.1152/ajprenal.90243.2008 [Abstract] [Full Text] [PDF]  

Tania Veuthey, María Cecilia D'Anna, and Marta Elena Roque

Role of the kidney in iron homeostasis: renal expression of Prohepcidin, Ferroportin, and DMT1 in anemic mice
Am J Physiol Renal Physiol 295: F1213-F1221, 2008. First published July 23, 2008; doi:10.1152/ajprenal.90216.2008 [Abstract] [Full Text] [PDF]  

Virginie Gaillard, Bernard Jover, Daniel Casellas, Magali Cordaillat, Jeffrey Atkinson, and Isabelle Lartaud

Renal function and structure in a rat model of arterial calcification and increased pulse pressure
Am J Physiol Renal Physiol 295: F1222-F1229, 2008. First published August 20, 2008; doi:10.1152/ajprenal.00081.2008 [Abstract] [Full Text] [PDF]  

Soo Mi Kim, Christoph Eisner, Robert Faulhaber-Walter, Diane Mizel, Susan M. Wall, Josephine P. Briggs, and Jurgen Schnermann

Salt sensitivity of blood pressure in NKCC1-deficient mice
Am J Physiol Renal Physiol 295: F1230-F1238, 2008. First published August 13, 2008; doi:10.1152/ajprenal.90392.2008 [Abstract] [Full Text] [PDF]  

Alaa E. S. Abdel-Razik, Richard J. Balment, and Nick Ashton

Enhanced renal sensitivity of the spontaneously hypertensive rat to urotensin II
Am J Physiol Renal Physiol 295: F1239-F1247, 2008. First published August 13, 2008; doi:10.1152/ajprenal.90374.2008 [Abstract] [Full Text] [PDF]  

Hui-Yi Chang and Leif A. Havton

Differential effects of urethane and isoflurane on external urethral sphincter electromyography and cystometry in rats
Am J Physiol Renal Physiol 295: F1248-F1253, 2008. First published August 27, 2008; doi:10.1152/ajprenal.90259.2008 [Abstract] [Full Text] [PDF]  

CALL FOR PAPERS:

Gustavo R. Ares, Paulo Caceres, Francisco J. Alvarez-Leefmans, and Pablo A. Ortiz

cGMP decreases surface NKCC2 levels in the thick ascending limb: role of phosphodiesterase 2 (PDE2)
Am J Physiol Renal Physiol 295: F877-F887, 2008. First published August 6, 2008; doi:10.1152/ajprenal.00449.2007 [Abstract] [Full Text] [PDF]  

Sheerazed Boulkroun, Dorothée Ruffieux-Daidié, Jean-Jacques Vitagliano, Olivier Poirot, Roch-Philippe Charles, Dagmara Lagnaz, Dmitri Firsov, Stephan Kellenberger, and Olivier Staub

Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3
Am J Physiol Renal Physiol 295: F889-F900, 2008. First published July 16, 2008; doi:10.1152/ajprenal.00001.2008 [Abstract] [Full Text] [PDF]  

REPORTS:

Michael L. Merchant, Timothy D. Cummins, Daniel W. Wilkey, Sarah A. Salyer, David W. Powell, Jon B. Klein, and Eleanor D. Lederer

Proteomic analysis of renal calculi indicates an important role for inflammatory processes in calcium stone formation
Am J Physiol Renal Physiol 295: F1254-F1258, 2008. First published August 13, 2008; doi:10.1152/ajprenal.00134.2008 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

REVIEWS:

Hayo Castrop and Jurgen Schnermann

Isoforms of renal Na-K-2Cl cotransporter NKCC2: expression and functional significance
Am J Physiol Renal Physiol 295: F859-F866, 2008. First published May 21, 2008; doi:10.1152/ajprenal.00106.2008 [Abstract] [Full Text] [PDF]  

Susanne Angelow, Robert Ahlstrom, and Alan S. L. Yu

Biology of claudins
Am J Physiol Renal Physiol 295: F867-F876, 2008. First published May 14, 2008; doi:10.1152/ajprenal.90264.2008 [Abstract] [Full Text] [PDF]  

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